Mr. DeRosa's Science Class

Part 1: The Romanov Pedigree

Romanov Genetics Activity Sheet

Signs & symptoms of spontaneous bleeding include:

• Unexplained and excessive bleeding from cuts or injuries, or after surgery or dental work

• Many large or deep bruises

• Unusual bleeding after vaccinations

• Pain, swelling or tightness in your joints

• Blood in your urine or stool

• Nosebleeds without a known cause

• In infants, unexplained irritability

Emergency signs & symptoms of hemophilia include:

• Sudden pain, swelling and warmth in large joints, such as knees, elbows, hips and shoulders, and in arm and leg muscles

• Bleeding from an injury, especially if a severe form of hemophilia

• Painful, prolonged headache

• Repeated vomiting

• Extreme fatigue

• Neck pain

• Double vision

A comparison of Hemophilia A with Normal clotting factor

Part 2: The Mystery of Anna Anderson

Part 3: Science Solves a Mystery